Incidence of temporary mechanical circulatory support before heart transplantation and impact on post-transplant outcomes

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The impact of mechanical circulatory support on outcomes in paediatric heart transplantation.

OBJECTIVES Internationally, the number of donors for cardiac transplantation has remained static, while the number of patients requiring transplantation for congenital heart disease (CHD) has increased. Although the availability of mechanical circulatory support (MCS) may increase the number of transplants performed by reducing deaths while waiting, it may also lead to increased morbidity post-...

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Mechanical circulatory support after paediatric heart transplantation.

OBJECTIVES Mechanical circulatory support (MCS) may be required after orthotopic heart transplantation (OHTx) in children for the treatment of failure or rejection. We review the incidence and outcomes of post-transplant MCS in our institution. METHODS MCS was classified as early (<1 month since transplant) or late (>1 month since transplant) and the support offered was either veno-arterial e...

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Chemotherapy-induced cardiomyopathy (CCMP) is a significant cause of morbidity and mortality. Compared to cardiomyopathy due to other causes, anthracycline-induced cardiomyopathy is associated with a worse survival. As cancer survival improves, patients with CCMP can be expected to comprise a significant proportion of patients who may require advanced therapies such as inotropic support, cardia...

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Limited mechanical circulatory support following orthotopic heart transplantation.

Shortage of donors enhances harvesting of borderline hearts. When such organs fail, a ventricular assist device may salvage the patient waiting for either recovery or for retransplantation. We describe a series of 12 patients who required circulatory support following orthotopic heart transplantation, with the use of four different devices. Four patients survived. The aim of this study is to de...

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Congestive heart failure is not a specific disease but rather a clinical syndrome of diverse etiologies. This syndrome is characterized by ventricular dysfunction leading to decreased cardiac output; consequent neurohumoral activation leading to salt and water retention, with congestion in the pulmonary and systemic circulation; a “vicious circle” of blood-flow maldistribution; and eventual hyp...

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ژورنال

عنوان ژورنال: The Journal of Heart and Lung Transplantation

سال: 2018

ISSN: 1053-2498

DOI: 10.1016/j.healun.2018.04.008